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	autoimmune thyroiditis

Disease ID	66
Disease	autoimmune thyroiditis
Definition	progressive enlargement of the thyroid gland, often associated with hypothyroidism.
Synonym	autoimmune lymphocytic chronic thyroiditis autoimmune thyroiditides chr lymphocyt thyroidit chronic lymphocytic thyroiditides chronic lymphocytic thyroiditis disease, hashimoto disease, hashimoto's hashimoto dis hashimoto disease hashimoto disease [disease/finding] hashimoto struma hashimoto syndrome hashimoto thyroiditides hashimoto thyroiditis hashimoto thyroiditis (disorder) hashimoto's disease hashimoto's struma hashimoto's syndrome hashimoto's syndromes hashimoto's thyroiditis hashimoto's thyroiditis (disorder) hashimotos dis hashimotos disease hashimotos syndrome lymphocytic thyroiditides, chronic lymphocytic thyroiditis lymphocytic thyroiditis, chronic lymphomatous thyroiditis struma lymphomatosa struma lymphomatosis struma lymphomatosis (disorder) syndrome, hashimoto's syndromes, hashimoto's thyroiditides, chronic lymphocytic thyroiditides, hashimoto thyroiditis chronic lymphocytic thyroiditis chronic lymphocytic hashimotos thyroiditis, chronic lymphadenoid thyroiditis, chronic lymphocytic thyroiditis, hashimoto thyroiditis, lymphoid
OMIM	OMIM:140300
DOID	DOID:7188
ICD10	ICD10CM:E06.3
UMLS	C0677607
MeSH	D050031
SNOMED-CT	SNOMEDCT_US_2016_09_01:21983002
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:139) C0020676 \| hypothyroidism \| 45 C0007115 \| thyroid ca \| 41 C0549473 \| thyroid carcinoma \| 27 C0238463 \| papillary thyroid carcinoma \| 20 C0007115 \| thyroid cancer \| 15 C0040137 \| thyroid nodule \| 14 C0040137 \| thyroid nodules \| 12 C0011847 \| diabetes \| 12 C0020676 \| hypothyroid \| 11 C0024299 \| lymphoma \| 8 C0011849 \| diabetes mellitus \| 7 C0011854 \| type 1 diabetes \| 7 C0007133 \| papillary carcinoma \| 6 C0010403 \| cryoglobulinemia \| 5 C0238463 \| papillary thyroid cancer \| 5 C0019158 \| hepatitis \| 5 C0019196 \| hepatitis c \| 4 C0020550 \| hyperthyroidism \| 4 C0021053 \| immune disorder \| 4 C0017152 \| gastritis \| 4 C0011854 \| type 1 diabetes mellitus \| 4 C1336753 \| thyroid lymphoma \| 3 C0032460 \| polycystic ovary syndrome \| 3 C0007570 \| celiac disease \| 3 C0042900 \| vitiligo \| 3 C0032460 \| polycystic ovary \| 3 C0021053 \| immune disease \| 3 C0018021 \| goiter \| 3 C0040147 \| thyroiditis \| 2 C0242647 \| malt lymphoma \| 2 C0001403 \| addison's disease \| 2 C0238462 \| medullary thyroid carcinoma \| 2 C0241910 \| autoimmune hepatitis \| 2 C0745140 \| hyperthyroid \| 2 C0001430 \| adenoma \| 2 C0040128 \| thyroid disease \| 2 C0011633 \| dermatomyositis \| 2 C0162855 \| mucinosis \| 2 C0018021 \| struma \| 2 C0042164 \| uveitis \| 2 C0027145 \| myxedema \| 2 C0038478 \| struma ovarii \| 2 C0042769 \| virus infection \| 2 C0002171 \| alopecia areata \| 2 C0024299 \| lymphomas \| 2 C0040156 \| thyrotoxicosis \| 2 C0021053 \| immune disorders \| 2 C0238463 \| thyroid papillary carcinoma \| 2 C0001623 \| hypoadrenalism \| 2 C0409974 \| lupus erythematosus \| 2 C0042109 \| urticaria \| 1 C0003469 \| anxiety disorder \| 1 C0020428 \| aldosteronism \| 1 C0000809 \| recurrent miscarriages \| 1 C0037198 \| sinus thrombosis \| 1 C0003467 \| anxiety \| 1 C0022658 \| nephropathy \| 1 C0149925 \| small cell lung cancer \| 1 C0948265 \| metabolic syndrome \| 1 C0017658 \| glomerulonephritis \| 1 C0027538 \| necrobiosis lipoidica \| 1 C1384514 \| primary aldosteronism \| 1 C0677607 \| hashimoto's disease \| 1 C0003469 \| anxiety disorders \| 1 C0038220 \| status epilepticus \| 1 C0003873 \| rheumatoid arthritis \| 1 C0041408 \| turner's syndrome \| 1 C0242647 \| mucosa-associated lymphoid tissue lymphoma \| 1 C0031039 \| pericardial effusion \| 1 C0014038 \| encephalitis \| 1 C0342388 \| adrenocorticotropic hormone deficiency \| 1 C0011570 \| depression \| 1 C0314719 \| dry eye \| 1 C0037928 \| myelopathy \| 1 C0000786 \| miscarriage \| 1 C0036421 \| systemic sclerosis \| 1 C1527336 \| sjogren's syndrome \| 1 C0235618 \| proliferative glomerulonephritis \| 1 C0018021 \| goitre \| 1 C0040053 \| thrombosis \| 1 C0026848 \| myopathy \| 1 C0002170 \| alopecia \| 1 C0020541 \| portal hypertension \| 1 C0086692 \| benign neoplasms \| 1 C0040149 \| subacute thyroiditis \| 1 C0042769 \| viral infection \| 1 C0022951 \| lactose intolerance \| 1 C0162836 \| hidradenitis suppurativa \| 1 C0346303 \| tshoma \| 1 C0003864 \| arthritis \| 1 C0085253 \| adult-onset still's disease \| 1 C0000809 \| recurrent miscarriage \| 1 C0020640 \| hypoprothrombinemia \| 1 C0018022 \| simple goiter \| 1 C0013338 \| growth hormone deficiency \| 1 C0878544 \| cardiomyopathy \| 1 C0039446 \| telangiectasia \| 1 C0004134 \| ataxia \| 1 C0002871 \| anaemia \| 1 C0018213 \| graves' disease \| 1 C1336753 \| lymphoma of the thyroid gland \| 1 C0085655 \| polymyositis \| 1 C0023522 \| metachromatic leukodystrophy \| 1 C0029089 \| ophthalmoplegia \| 1 C0206138 \| crest syndrome \| 1 C0025235 \| melkersson-rosenthal syndrome \| 1 C0151468 \| thyroid adenoma \| 1 C0007133 \| papillary carcinomas \| 1 C0152113 \| sydenham's chorea \| 1 C0272126 \| evans syndrome \| 1 C0085113 \| neurofibromatosis \| 1 C0242379 \| lung cancer \| 1 C0011644 \| scleroderma \| 1 C0010068 \| coronary heart disease \| 1 C0033806 \| pseudohypoparathyroidism \| 1 C0002892 \| pernicious anaemia \| 1 C0018378 \| guillain barre syndrome \| 1 C0085215 \| premature ovarian failure \| 1 C0339143 \| thyroid-associated ophthalmopathy \| 1 C0086692 \| benign neoplasm \| 1 C0017665 \| membranous nephropathy \| 1 C0004135 \| ataxia telangiectasia \| 1 C0024141 \| systemic lupus erythematosus \| 1 C0085273 \| parvovirus b19 infection \| 1 C0000786 \| miscarriages \| 1 C0085160 \| hidradenitis \| 1 C0015464 \| facial palsy \| 1 C0017154 \| atrophic gastritis \| 1 C0011854 \| insulin-dependent diabetes \| 1 C0677607 \| hashimoto's thyroiditis \| 1 C0023520 \| leukodystrophy \| 1 C0018799 \| heart disease \| 1 C0085293 \| hepatitis e \| 1 C0079774 \| peripheral t-cell lymphoma \| 1 C0242647 \| mucosa-associated lymphoid tissue \| 1 C0262587 \| parathyroid adenoma \| 1 C0017662 \| membranoproliferative glomerulonephritis \| 1 C0011854 \| insulin-dependent diabetes mellitus \| 1 C0011649 \| dermoid cyst \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:8) 3123 \| HLA-DRB1 \| GHR 7038 \| TG \| CTD_human;GHR 1493 \| CTLA4 \| CTD_human;GHR 7253 \| TSHR \| CTD_human 115352 \| FCRL3 \| CTD_human 716 \| C1S \| CTD_human 2215 \| FCGR3B \| UNIPROT 57623 \| ZFAT \| CTD_human
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:20) 1734 \| DIO2 \| CIPHER 3117 \| HLA-DQA1 \| CIPHER 3119 \| HLA-DQB1 \| CIPHER 3123 \| HLA-DRB1 \| CIPHER 3553 \| IL1B \| CIPHER 3557 \| IL1RN \| CIPHER 3569 \| IL6 \| CIPHER 7124 \| TNF \| CIPHER 7421 \| VDR \| CIPHER 1493 \| CTLA4 \| CIPHER;CTD_human 3126 \| HLA-DRB4 \| CIPHER 7038 \| TG \| CIPHER;CTD_human 115352 \| FCRL3 \| CTD_human 716 \| C1S \| CTD_human 7253 \| TSHR \| CTD_human 140805 \| HT \| CTD_human 387579 \| AITD2 \| CTD_human 387578 \| AITD1 \| CTD_human 387581 \| AITD4 \| CTD_human 57623 \| ZFAT \| CTD_human
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:134) 58 \| ACTA1 \| 1.132 \| DISEASES 164 \| AP1G1 \| 1.235 \| DISEASES 54828 \| BCAS3 \| 1.279 \| DISEASES 440603 \| BCL2L15 \| 1.774 \| DISEASES 65980 \| BRD9 \| 1.415 \| DISEASES 721 \| C4B \| 1.185 \| DISEASES 796 \| CALCA \| 3.757 \| DISEASES 844 \| CASQ1 \| 3.446 \| DISEASES 1235 \| CCR6 \| 1.047 \| DISEASES 930 \| CD19 \| 2.239 \| DISEASES 917 \| CD3G \| 1.521 \| DISEASES 958 \| CD40 \| 3.288 \| DISEASES 959 \| CD40LG \| 3.453 \| DISEASES 921 \| CD5 \| 2.504 \| DISEASES 965 \| CD58 \| 1.039 \| DISEASES 942 \| CD86 \| 1.313 \| DISEASES 1041 \| CDSN \| 1.912 \| DISEASES 23274 \| CLEC16A \| 1.261 \| DISEASES 441521 \| CT45A5 \| 3.465 \| DISEASES 4283 \| CXCL9 \| 2.944 \| DISEASES 2833 \| CXCR3 \| 2.6 \| DISEASES 51428 \| DDX41 \| 4.124 \| DISEASES 1734 \| DIO2 \| 1.937 \| DISEASES 135656 \| DPCR1 \| 1.259 \| DISEASES 50506 \| DUOX2 \| 1.094 \| DISEASES 6993 \| DYNLT1 \| 1.691 \| DISEASES 116496 \| FAM129A \| 1.295 \| DISEASES 355 \| FAS \| 1.612 \| DISEASES 356 \| FASLG \| 3.904 \| DISEASES 2214 \| FCGR3A \| 1.549 \| DISEASES 115350 \| FCRL1 \| 1.843 \| DISEASES 115352 \| FCRL3 \| 2.221 \| DISEASES 84824 \| FCRLA \| 1.106 \| DISEASES 2316 \| FLNA \| 1.225 \| DISEASES 2317 \| FLNB \| 2.794 \| DISEASES 27022 \| FOXD3 \| 1.076 \| DISEASES 2304 \| FOXE1 \| 1.946 \| DISEASES 50943 \| FOXP3 \| 3.581 \| DISEASES 2520 \| GAST \| 1.782 \| DISEASES 2638 \| GC \| 1.977 \| DISEASES 51738 \| GHRL \| 1.504 \| DISEASES 2878 \| GPX3 \| 1.225 \| DISEASES 51696 \| HECA \| 2.111 \| DISEASES 8346 \| HIST1H2BI \| 1.24 \| DISEASES 8337 \| HIST2H2AA3 \| 2.963 \| DISEASES 317772 \| HIST2H2AB \| 3.289 \| DISEASES 8338 \| HIST2H2AC \| 2.963 \| DISEASES 8349 \| HIST2H2BE \| 2.051 \| DISEASES 3105 \| HLA-A \| 2.928 \| DISEASES 3115 \| HLA-DPB1 \| 2.127 \| DISEASES 3117 \| HLA-DQA1 \| 3.165 \| DISEASES 3118 \| HLA-DQA2 \| 1.735 \| DISEASES 3119 \| HLA-DQB1 \| 2.173 \| DISEASES 3120 \| HLA-DQB2 \| 1.404 \| DISEASES 3122 \| HLA-DRA \| 2.079 \| DISEASES 3123 \| HLA-DRB1 \| 2.487 \| DISEASES 3127 \| HLA-DRB5 \| 1.208 \| DISEASES 3305 \| HSPA1L \| 1.559 \| DISEASES 3339 \| HSPG2 \| 1.794 \| DISEASES 3384 \| ICAM2 \| 1.099 \| DISEASES 3456 \| IFNB1 \| 1.656 \| DISEASES 100885789 \| IFNG-AS1 \| 2.466 \| DISEASES 3586 \| IL10 \| 3.369 \| DISEASES 3605 \| IL17A \| 2.715 \| DISEASES 3559 \| IL2RA \| 3.051 \| DISEASES 3570 \| IL6R \| 1.08 \| DISEASES 3683 \| ITGAL \| 1.21 \| DISEASES 3684 \| ITGAM \| 1.356 \| DISEASES 3880 \| KRT19 \| 2.873 \| DISEASES 3898 \| LAD1 \| 1.739 \| DISEASES 79168 \| LILRA6 \| 1.576 \| DISEASES 348120 \| LINC01193 \| 3.446 \| DISEASES 4049 \| LTA \| 2.18 \| DISEASES 4311 \| MME \| 1.031 \| DISEASES 143662 \| MUC15 \| 2.174 \| DISEASES 4593 \| MUSK \| 1.664 \| DISEASES 83463 \| MXD3 \| 1.444 \| DISEASES 10004 \| NAALADL1 \| 1.482 \| DISEASES 8031 \| NCOA4 \| 3.667 \| DISEASES 7080 \| NKX2-1 \| 1.707 \| DISEASES 170685 \| NUDT10 \| 2.522 \| DISEASES 4942 \| OAT \| 1.692 \| DISEASES 5125 \| PCSK5 \| 1.201 \| DISEASES 10745 \| PHTF1 \| 1.734 \| DISEASES 8301 \| PICALM \| 3.587 \| DISEASES 5406 \| PNLIP \| 1.252 \| DISEASES 5646 \| PRSS3 \| 6.41 \| DISEASES 11168 \| PSIP1 \| 1.711 \| DISEASES 5696 \| PSMB8 \| 1.468 \| DISEASES 5698 \| PSMB9 \| 1.323 \| DISEASES 5727 \| PTCH1 \| 2.893 \| DISEASES 5728 \| PTEN \| 1.355 \| DISEASES 5783 \| PTPN13 \| 1.236 \| DISEASES 26191 \| PTPN22 \| 4.458 \| DISEASES 5788 \| PTPRC \| 1.65 \| DISEASES 84109 \| QRFPR \| 1.964 \| DISEASES 5979 \| RET \| 3.644 \| DISEASES 6023 \| RMRP \| 1.43 \| DISEASES 8635 \| RNASET2 \| 1.184 \| DISEASES 6279 \| S100A8 \| 1.42 \| DISEASES 80274 \| SCUBE1 \| 1.274 \| DISEASES 51150 \| SDF4 \| 2.489 \| DISEASES 10500 \| SEMA6C \| 1.051 \| DISEASES 866 \| SERPINA6 \| 1.839 \| DISEASES 6906 \| SERPINA7 \| 2.623 \| DISEASES 55532 \| SLC30A10 \| 2.256 \| DISEASES 169026 \| SLC30A8 \| 1.979 \| DISEASES 153201 \| SLC36A2 \| 1.268 \| DISEASES 64094 \| SMOC2 \| 1.207 \| DISEASES 23583 \| SMUG1 \| 1.827 \| DISEASES 26812 \| SNORD37 \| 1.756 \| DISEASES 26807 \| SNORD43 \| 1.404 \| DISEASES 692076 \| SNORD7 \| 1.58 \| DISEASES 26770 \| SNORD79 \| 1.741 \| DISEASES 692225 \| SNORD94 \| 2.519 \| DISEASES 6693 \| SPN \| 2.047 \| DISEASES 6430 \| SRSF5 \| 1.876 \| DISEASES 6775 \| STAT4 \| 1.031 \| DISEASES 3703 \| STT3A \| 1.206 \| DISEASES 27004 \| TCL6 \| 1.763 \| DISEASES 7052 \| TGM2 \| 2.952 \| DISEASES 7068 \| THRB \| 1.841 \| DISEASES 7124 \| TNF \| 3.347 \| DISEASES 8784 \| TNFRSF18 \| 1.692 \| DISEASES 8718 \| TNFRSF25 \| 4.525 \| DISEASES 7293 \| TNFRSF4 \| 1.07 \| DISEASES 10673 \| TNFSF13B \| 1.589 \| DISEASES 1861 \| TOR1A \| 2.542 \| DISEASES 10587 \| TXNRD2 \| 2.387 \| DISEASES 7306 \| TYRP1 \| 1.063 \| DISEASES 7421 \| VDR \| 2.722 \| DISEASES 8875 \| VNN2 \| 1.404 \| DISEASES 57623 \| ZFAT \| 2.426 \| DISEASES 162239 \| ZFP1 \| 1.139 \| DISEASES
Locus	(Waiting for update.)

Disease ID	66
Disease	autoimmune thyroiditis
Integrated Phenotype	HPO \| Name(Total Integrated Phenotypes:2) HP:0030057 \| Autoimmune antibody positivity HP:0000872 \| Hashimoto's thyroiditis
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:85) HP:0000821 \| Underactive thyroid \| 50 HP:0001298 \| Encephalopathy \| 28 HP:0002890 \| Thyroid carcinoma \| 27 HP:0030731 \| Carcinoma \| 24 HP:0002895 \| Papillary thyroid carcinoma \| 21 HP:0002665 \| Lymphoma \| 10 HP:0002960 \| Autoimmune condition \| 8 HP:0000832 \| Primary hypothyroidism \| 8 HP:0000819 \| Diabetes mellitus \| 8 HP:0000836 \| Overactive thyroid \| 5 HP:0012115 \| Liver inflammation \| 5 HP:0100778 \| Cryoglobulinemia \| 5 HP:0005263 \| Gastritis \| 4 HP:0000853 \| Goitre \| 4 HP:0100646 \| Thyroiditis \| 4 HP:0002608 \| Celiac disease \| 3 HP:0002664 \| Neoplasia \| 3 HP:0001045 \| Blotchy loss of skin color \| 3 HP:0000147 \| Sclerocystic ovaries \| 3 HP:0100028 \| Abnormal thryoid location \| 2 HP:0008207 \| Addison's disease \| 2 HP:0001903 \| Anemia \| 2 HP:0000820 \| Thyroid abnormality \| 2 HP:0002865 \| Medullary thyroid carcinoma \| 2 HP:0012190 \| T cell lymphoma \| 2 HP:0000554 \| Uveitis \| 2 HP:0200123 \| Chronic liver inflammation \| 2 HP:0000846 \| Hypoadrenalism \| 2 HP:0002835 \| Aspiration \| 2 HP:0001025 \| Hives \| 2 HP:0002229 \| Alopecia areata \| 2 HP:0002716 \| Lymph node hyperplasia \| 2 HP:0002897 \| Parathyroid adenoma \| 1 HP:0008209 \| Premature ovarian failure \| 1 HP:0010628 \| Facial palsy, unilateral or bilateral \| 1 HP:0000854 \| Thyroid adenoma \| 1 HP:0001596 \| Hair loss \| 1 HP:0003201 \| Rhabdomyolysis \| 1 HP:0001370 \| Rheumatoid arthritis \| 1 HP:0200040 \| Epidermal inclusion cyst \| 1 HP:0000716 \| Depression \| 1 HP:0000739 \| Anxiety \| 1 HP:0030833 \| Neck pain \| 1 HP:0002725 \| Systemic lupus erythematosus \| 1 HP:0002133 \| Status epilepticus \| 1 HP:0000602 \| Ophthalmoplegia \| 1 HP:0001009 \| Telangiectases \| 1 HP:0200028 \| Pretibial myxedema \| 1 HP:0001067 \| Neurofibromas \| 1 HP:0002930 \| Resistance to thyroid hormone \| 1 HP:0003198 \| Myopathic changes \| 1 HP:0001369 \| Arthritis \| 1 HP:0100324 \| Progressive systemic scleroderma \| 1 HP:0003002 \| Breast carcinoma \| 1 HP:0001698 \| Pericardial effusions \| 1 HP:0000872 \| Hashimoto's thyroiditis \| 1 HP:0040154 \| Hidradenitis suppurativa \| 1 HP:0000793 \| Membranoproliferative glomerulonephritis \| 1 HP:0000852 \| Pseudohypoparathyroidism \| 1 HP:0000099 \| Glomerular nephritis \| 1 HP:0100029 \| Lingual thyroid \| 1 HP:0004789 \| Lactose intolerance \| 1 HP:0003493 \| Elevated antinuclear antibody \| 1 HP:0000870 \| Hyperprolactinemia \| 1 HP:0011780 \| Thyroid hemiagenesis \| 1 HP:0000112 \| Nephropathy \| 1 HP:0012578 \| Membranous glomerulonephritis \| 1 HP:0002072 \| Chorea \| 1 HP:0001251 \| Ataxia \| 1 HP:0002383 \| Encephalitis \| 1 HP:0001409 \| Portal hypertension \| 1 HP:0002415 \| Degeneration of white matter of brain \| 1 HP:0001297 \| Cerebral vascular events \| 1 HP:0012531 \| Pain \| 1 HP:0000544 \| CPEO \| 1 HP:0000824 \| Growth hormone deficiency \| 1 HP:0005202 \| Helicobacter pylori infection \| 1 HP:0011748 \| Adrenocorticotropic hormone deficiency \| 1 HP:0001919 \| Acute renal failure \| 1 HP:0100315 \| Lewy bodies \| 1 HP:0006846 \| Acute encephalopathy \| 1 HP:0002196 \| Myelopathy \| 1 HP:0200058 \| Angiosarcoma \| 1 HP:0030357 \| Small cell lung carcinoma \| 1 HP:0001638 \| Cardiomyopathy \| 1

Disease ID	66
Disease	autoimmune thyroiditis
Manually Symptom	UMLS \| Name(Total Manually Symptoms:33) C2186740 \| urticaria C2062356 \| idiopathic portal hypertension C1963101 \| encephalopathy C1527336 \| sjogren's disease C0700502 \| primary hypothyroidism C0549473 \| thyroid cancer C0348024 \| thyroid dysfunction C0342122 \| diffuse toxic goiter C0271795 \| transient hypothyroidism C0271791 \| severe hypothyroidism C0271790 \| subclinical hypothyroidism C0264005 \| eosinophilic fasciitis C0262548 \| maternal hypothyroidism C0238463 \| papillary thyroid carcinoma C0220847 \| hepatitis c C0085655 \| polymyositis C0040156 \| thyrotoxicosis C0040137 \| thyroid nodules C0039263 \| takayasu's disease C0039263 \| takayasu's arteritis C0036421 \| systemic sclerosis C0029401 \| paget's disease of bone C0021053 \| immune disorders C0020676 \| hypothyroidism C0020555 \| hypertrichosis C0020550 \| hyperthyroidism C0020097 \| htlv-i infection C0017662 \| membranoproliferative glomerulonephritis C0013080 \| trisomy 21 C0011860 \| diabetes C0011854 \| insulin-dependent diabetes mellitus C0007570 \| coeliac disease C0007570 \| celiac disease
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:43) C0020676 \| hypothyroidism \| 48 C0085584 \| encephalopathy \| 27 C0549473 \| thyroid carcinoma \| 20 C0238463 \| papillary thyroid carcinoma \| 16 C0271790 \| subclinical hypothyroidism \| 12 C0040137 \| thyroid nodules \| 11 C0011847 \| diabetes \| 11 C0007115 \| thyroid cancer \| 9 C0700502 \| primary hypothyroidism \| 8 C0020676 \| hypothyroid \| 6 C0007133 \| papillary carcinoma \| 5 C0024299 \| lymphoma \| 5 C0009450 \| infection \| 4 C1336753 \| lymphoma of the thyroid \| 4 C0271791 \| severe hypothyroidism \| 3 C0007570 \| celiac disease \| 3 C0019196 \| hepatitis c \| 3 C0042109 \| urticaria \| 2 C0040137 \| thyroid nodule \| 2 C0018021 \| goiter \| 2 C0022658 \| nephropathy \| 1 C0024228 \| lymphadenopathy \| 1 C0850666 \| helicobacter pylori infection \| 1 C0086776 \| parvovirus \| 1 C0011854 \| insulin-dependent diabetes mellitus \| 1 C0017662 \| membranoproliferative glomerulonephritis \| 1 C0021053 \| immune disorder \| 1 C0339143 \| thyroid-associated ophthalmopathy \| 1 C0013338 \| growth hormone deficiency \| 1 C0037928 \| myelopathy \| 1 C0006142 \| breast cancer \| 1 C0029089 \| ophthalmoplegia \| 1 C0348024 \| thyroid dysfunction \| 1 C0036421 \| systemic sclerosis \| 1 C0024141 \| systemic lupus erythematosus \| 1 C0003873 \| rheumatoid arthritis \| 1 C0079772 \| t-cell lymphoma \| 1 C0020514 \| hyperprolactinemia \| 1 C0241910 \| autoimmune hepatitis \| 1 C0206138 \| crest syndrome \| 1 C0020550 \| hyperthyroidism \| 1 C0085273 \| parvovirus b19 infection \| 1 C0001430 \| adenoma \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

Text Mining Genotype(Total Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:17)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs1042031	25587205	4547	MTTP	umls:C0677607	BeFree	We analyzed the associations of seven polymorphisms of genes involved in lipid metabolism (APOA5 rs3135506, APOB rs1042031, FABP2 rs1799883, LDLR rs5925, LIPC rs1800588, LPL rs328, and MTTP rs1800591) with blood pressure and lipid values in Mexican hypertensive (HT) patients.	0.000271442	2014	APOB	2	21002881	C	T,A
rs113488022	19014278	673	BRAF	umls:C0677607	BeFree	Clinical and pathological features and the BRAF(V600E) mutation in patients with papillary thyroid carcinoma with and without concurrent Hashimoto thyroiditis.	0.009001189	2009	BRAF	7	140753336	A	T,G,C
rs113488022	24721322	673	BRAF	umls:C0677607	BeFree	We analyzed the correlation between the presence/absence of the BRAF(V600E) mutation in the fine-needle aspiration (FNA) and the clinical-pathological features: age, gender, extension of surgery, node dissection, rate of cervical lymph node involvement, tumor size, TNM stage, variant of histotype, mono/plurifocality, association with lymphocitary chronic thyroiditis, radioactive iodine ablation doses, and outcome.	0.009001189	2014	BRAF	7	140753336	A	T,G,C
rs113488022	18426810	673	BRAF	umls:C0677607	BeFree	Screening for activating BRAF mutations in a series of 83 PTCs identified the most common V600E mutation in 39 cases (histologically, 38 classic PTCs and 1 sclerosing variant PTC) and a complex in-frame mutation involving amino acids V600-S605 in a stage III multicentric follicular variant PTC, occurring in a 50-year-old female patient, who was affected by hypothyroidism in autoimmune thyroiditis and had a family history of PTC and autoimmune thyroiditis.	0.009001189	2008	BRAF	7	140753336	A	T,G,C
rs113488022	18426810	673	BRAF	umls:C0920350	BeFree	Screening for activating BRAF mutations in a series of 83 PTCs identified the most common V600E mutation in 39 cases (histologically, 38 classic PTCs and 1 sclerosing variant PTC) and a complex in-frame mutation involving amino acids V600-S605 in a stage III multicentric follicular variant PTC, occurring in a 50-year-old female patient, who was affected by hypothyroidism in autoimmune thyroiditis and had a family history of PTC and autoimmune thyroiditis.	0.000542884	2008	BRAF	7	140753336	A	T,G,C
rs1799883	25587205	4547	MTTP	umls:C0677607	BeFree	We analyzed the associations of seven polymorphisms of genes involved in lipid metabolism (APOA5 rs3135506, APOB rs1042031, FABP2 rs1799883, LDLR rs5925, LIPC rs1800588, LPL rs328, and MTTP rs1800591) with blood pressure and lipid values in Mexican hypertensive (HT) patients.	0.000271442	2014	FABP2	4	119320747	T	G,C,A
rs1800588	25587205	4547	MTTP	umls:C0677607	BeFree	We analyzed the associations of seven polymorphisms of genes involved in lipid metabolism (APOA5 rs3135506, APOB rs1042031, FABP2 rs1799883, LDLR rs5925, LIPC rs1800588, LPL rs328, and MTTP rs1800591) with blood pressure and lipid values in Mexican hypertensive (HT) patients.	0.000271442	2014	LIPC;LOC102724766	15	58431476	C	T
rs1800591	25587205	4547	MTTP	umls:C0677607	BeFree	We analyzed the associations of seven polymorphisms of genes involved in lipid metabolism (APOA5 rs3135506, APOB rs1042031, FABP2 rs1799883, LDLR rs5925, LIPC rs1800588, LPL rs328, and MTTP rs1800591) with blood pressure and lipid values in Mexican hypertensive (HT) patients.	0.000271442	2014	MTTP	4	99574331	G	T
rs231775	21503616	1493	CTLA4	umls:C0677607	BeFree	CTLA4 exon1 A49G polymorphism in Slovak patients with rheumatoid arthritis and Hashimoto thyroiditis-results and the review of the literature.	0.149181152	2011	CTLA4	2	203867991	A	G,T
rs2476601	20438787	26191	PTPN22	umls:C0920350	BeFree	To evaluate the prevalence of PTPN22 C1858T polymorphism in young type 1 diabetes patients with or without autoimmune thyroiditis.	0.00764398	2010	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2476601	20438787	26191	PTPN22	umls:C0677607	BeFree	To evaluate the prevalence of PTPN22 C1858T polymorphism in young type 1 diabetes patients with or without autoimmune thyroiditis.	0.005276948	2010	PTPN22;AP4B1-AS1	1	113834946	A	G
rs3087243	24697361	1493	CTLA4	umls:C0677607	BeFree	Taken together, our study suggested that the CT60 polymorphism (rs3087243) in CTLA-4 gene might confer susceptibility to the AITDs (GD/HT).	0.149181152	2015	CTLA4	2	203874196	G	A
rs3087243	24697361	348120	LINC01193	umls:C0677607	BeFree	Taken together, our study suggested that the CT60 polymorphism (rs3087243) in CTLA-4 gene might confer susceptibility to the AITDs (GD/HT).	0.000814326	2015	CTLA4	2	203874196	G	A
rs3135506	25587205	4547	MTTP	umls:C0677607	BeFree	We analyzed the associations of seven polymorphisms of genes involved in lipid metabolism (APOA5 rs3135506, APOB rs1042031, FABP2 rs1799883, LDLR rs5925, LIPC rs1800588, LPL rs328, and MTTP rs1800591) with blood pressure and lipid values in Mexican hypertensive (HT) patients.	0.000271442	2014	APOA5	11	116791691	G	A,C
rs328	25587205	4547	MTTP	umls:C0677607	BeFree	We analyzed the associations of seven polymorphisms of genes involved in lipid metabolism (APOA5 rs3135506, APOB rs1042031, FABP2 rs1799883, LDLR rs5925, LIPC rs1800588, LPL rs328, and MTTP rs1800591) with blood pressure and lipid values in Mexican hypertensive (HT) patients.	0.000271442	2014	LPL	8	19962213	C	G
rs3792876	26329403	6583	SLC22A4	umls:C0677607	BeFree	The aim of this study is to investigate whether SNP rs3792876 in the SLC22A4 gene is associated with GD, HT and AITD in a Chinese Han population.	0.000271442	2015	SLC22A4	5	132301616	C	T
rs5925	25587205	4547	MTTP	umls:C0677607	BeFree	We analyzed the associations of seven polymorphisms of genes involved in lipid metabolism (APOA5 rs3135506, APOB rs1042031, FABP2 rs1799883, LDLR rs5925, LIPC rs1800588, LPL rs328, and MTTP rs1800591) with blood pressure and lipid values in Mexican hypertensive (HT) patients.	0.000271442	2014	LDLR	19	11120205	T	C

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:1)
HP ID	HP Name	MP ID	MP Name	Annotation
HP:0000872	Hashimoto thyroiditis	MP:0012431	increased lymphoma incidence	greater than the expected number of neoplasms characterized by a proliferation of malignant lymphocytes in lymphoid tissue in a specific population in a given time period

Disease ID	66
Disease	autoimmune thyroiditis
Case	(Waiting for update.)

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